9 Steps To Perfect Health, Chris Kresser — chriskresser.com/perfect-health

"But while allopathic medicine excels at emergency and trauma care, it isn't very good at fostering health. (In fact the subject of health rarely comes up at all in conventional medical textbooks, which are entirely focused on disease.) ... One of the most glaring mistakes conventional medicine makes is to assume that all of these modern diseases—diabetes, heart disease, depression, autoimmune disease, etc.—are unrelated conditions that don't share a common cause. ... The conventional approach is to treat each of these various problems with different drug[sic], and ignore the fundamental factors that are at the root of all of them. That has been a stupendously unsuccessful approach."

11 Charts That Show Everything Wrong with Our Modern Diet — articles.mercola.com/sites/articles/archive/2014/02/24/modern-diet.aspx

L-METHYL FOLATE SUPPLEMENTATION, by Dr. Carol S. Savage, MD — L-Methyl_Folate.doc [See: FOLATE]

NUTRITIONAL PROTOCOL [ — www.rawlins.org/mthfr/MTHFR%20protocol.doc]

"It is associated with problems such as early heart disease, stroke, blood clots, depression, anxiety, irritable bowel syndrome (IBS), fibromyalgia, chronic fatigue, chronic pain, migraines as well as heavy metal and other environment toxin retention."

The mitochondrial tune-up -Part I: Nutrients Required for Mitochondrial Energy Production (Optimal Nutrition for Mitochondrial Function) — www.lmreview.com/articles/view/beyond-the-mitochondrial-tune-up-part-I/

The mitochondrial tune-up -Part I: Optimal Nutrition for Mitochondrial Function — www.lmreview.com/articles/view/beyond-the-mitochondrial-tune-up-part-II/

Methyl Cycle Nutrigenomics and food lists to support methylation cycles — www.heartfixer.com/AMRI-Outcomes-Non-CV-Autism-Methyl%20Cycle.htm#MTRR:%C2%A0%20Methionine%20Synthase%20Reductase

Video: Targeted Nutrition Based Upon Your Own Unique DNA — vimeo.com/user20863995/review/90477798/a91b3b2a44

Audio files: Coffee With Dr. Stewart - Neurotologist & Genomic Specialist —

10 Health Tips for Anyone with a MTHFR Gene Mutation, Jill Carnahan, MD, ABFM, ABIHM, IFMCP — www.jillcarnahan.com/2014/02/23/health-tips-for-anyone-with-a-mthfr-gene-mutation/

[See: Gluten free foods and recipes]

*** Recommendations for C677T allele: — mthfr.net/mthfr-c677t-mutation-basic-protocol/2012/02/24/)

List of Amino Acids — www.homeopathyforwomen.org/amino_acids.htm

Methionine "Together with cysteine, methionine is one of two sulfur-containing proteinogenic amino acids. Its derivative S-adenosyl methionine (SAM) serves as a methyl donor. ..
Methionine is an intermediate in the biosynthesis of cysteine, carnitine, taurine, lecithin, phosphatidylcholine, and other phospholipids. Methionine can be regenerated from homocysteine via methionine synthase in a reaction that requires Vitamin B12 as a cofactor." http://en.wikipedia.org/wiki/Methionine

Methionine [Other Names: DL-Methionine, L-2-amino-4-(methylthio)butyric acid, L-Methionine, Metionina.] (in its natural L-form) is a proteinogen amino acid, classed as an essential amino acid, and cannot be synthesized by the body. Methionine is found in meat, fish, and dairy products and it plays an important role in many cell functions. — nutritiondata.self.com/foods-000084000000000000000.html [See: INFECTIONS]

Betaine (Trimethyglycine [TMG]) "This medication is used to treat high levels of a certain important body chemical (homocysteine) due to an inherited disorder (homocystinuria). Decreasing high homocysteine levels may help prevent serious blood clots, abnormal bone formation, brittle bones (osteoporosis), and eye problems (e.g., dislocated eye lens, nearsightedness). This medication works by decreasing blood levels of homocysteine. It does not correct the inherited disorder that causes the disease." — www.webmd.com/drugs/drug-1558-betaine+oral.aspx

"The dramatic effects of betaine on survival and growth, and the partial reversibility of the biochemical and developmental anomalies in the brains of MTHFR-deficient mice, emphasize an important role for choline and betaine depletion in the pathogenesis of homocystinuria due to MTHFR deficiency. ...
Betaine supplementation has proven effective in ameliorating the biochemical abnormalities and the clinical course in homocystinuria due to severe MTHFR deficiency. It lowers the elevated plasma homocysteine levels associated with this disease and increases plasma methionine concentrations. Betaine supplementation is believed to directly enhance homocysteine remethylation and, consequently, to increase the availability of methionine for protein synthesis and transmethylation. However, high-dose betaine treatment does not normalize homocysteine metabolism in homocystinuric patients, as indicated by plasma homocysteine levels that remain 5-10-fold elevated." www.biochemj.org/bj/382/0831/3820831.pdf

Choline Choline is an essential nutrient and a precursor for betaine (Fig. 1). It has several important functions: a source of methyl groups needed to make the primary methyl donor, S-adenosylmethionine; a part of the neurotransmitter acetylcholine; and a component of the predominant phospholipids in membranes (phosphatidylcholine and sphingomyelin). Folate and choline are metabolically interrelated. Diminished folate availability increases demand for choline as a methyl donor while decreased choline availability increases demand for folate methyl groups. Choline, a water-soluble essential nutrient, helps keep the cells and nerves working normally. Choline and esters of choline are widely distributed in food; with animal products generally containing more choline per unit weight than plants. Sources are: eggs, beef, chicken, fish, and milk as well as select plant foods like cruciferous vegetables and certain beans.

Bill Sardi: the vitamin supplement answer man — knowledgeofhealth.com/

B-1 — Benfotiamine is a lipid-soluble form of thiamine (vitamin B-1). It is the most effective metabolic precursor of active thiamine, or vitamin B1, available. It metabolizes quickly, producing high levels of thiamine pyrophosphate (TPP, the active form of thiamine), which then continues to metabolize in the body as usual.

Niacinamide (B3) Benefits these problems: MRSA, Staph, Candida yeast overgrowth, arthritis, cancer, diabetes, depression, Schizophrenia, Alzheimers, and learning disabilities. — lymeinchronicillness.com/benefits-of-b3-niacinamide/ [See: DIABETES]

What's So Important about B12? — wholenewmom.com/health-concerns/b12-deficiency-liver-pills-how-to-make-liver-pills/

*** Vitamin C, Titrating to Tolerance by Robert F. Cathcart, M.D. — vitamincfoundation.org/www.orthomed.com/titrate.htm

"It is well established that certain symptoms are associated with an almost total lack of vitamin C within the body. Symptoms of scurvy include lassitude, malaise, bleeding gums, loss of teeth, nosebleeds, bruising, hemorrhages in any part of the body, easy infections, poor healing of wounds, deterioration of joints, brittle and painful bones, and death, etc. It is thought that this disease only occurs with dietary deprivation of vitamin C. However, an analogous condition is produced as follows:

Well-nourished humans usually contain not much more than 5 grams of vitamin C in their bodies. Unfortunately, the majority of people have far less ascorbate than this amount in their bodies and are at risk for many problems related to failure of metabolic processes dependent upon ascorbate. This condition is called CHRONIC SUBCLINICAL SCURVY."

These two quotes are instructive: "There are more than ten thousand scientific papers that make it quite clear that there is not one body process (such as what goes on inside cells or tissues) and not one disease or syndrome (from the common cold to leprosy) that is not influenced - directly or indirectly - by vitamin C." - Dr. Emanuel Cheraskin, M.D., Dr. Marshall Ringsdorf, D.M.D., and Dr. Emily Sisley, THE VITAMIN C CONNECTION.
"I have never seen a patient that Vitamin C would not benefit." - Dr. Frederick Klenner, M.D. [See: knowledgeofhealth.com/vitamin-c-in-the-emergency-department-nose-bleeds/

Vitamin C, magnesium, L-glutamine, zinc L-carnosine How to calm IBS without prescription drugs

Vitamin D Dose Recommendations, Dr. Mercola, MD: Ideally your blood level of 25 OH D should be 60ng/ml or greater.

Vitamin D sources are: milk, eggs, cod liver oil, shiitake mushrooms and certain fish including tuna. It is rarely possible to get enough vitamin D from diet alone. Even with supplementation it may take months to reach adequate levels, then take some Vitamin D3 daily for the rest of your life.

Inflammation and vitamin D: the infection connection from the National Center for Biotechnology Information, U.S. National Library of Medicine: www.ncbi.nlm.nih.gov/pmc/articles/PMC4160567/

Folate vs folic acid — chriskresser.com/folate-vs-folic-acid

Folate is essential for the synthesis of S-adenosylmethionine (SAMe), the main methyl donor required for methylation reactions in cells. 5-methyl folate [often denoted as L-MTHF, L-Methylfolate, L-5-MTHF, 6(S)-5-Methylfolate]

Folic acid supplements are not helpful (Benjamin Lynch, N.D.) — www.youtube.com/watch?v=Mwn7RjSx3zM

Methocobalamine (B12) and folic acid (Actifolate- more absorbable form) and 200 mcg of selenium (seleniomethionine form), a liquid B supplement- Sisel Spectro Max or Liquid B complex by Tropical Oasis, Evening Primrose oil and Krill oil. These supplements will help treat the pyroluria and the methylation problems. [See: Simplified Roadmap to Health — www.scribd.com/doc/132017201/Dr-Amy-s-Simplified-Road-Map-to-Health for finding correct form of B12 for you.

"Methylcobalamin (B12) (for B12 deficiency and Peripheral Neuropathy), [B-9 as folic acid and B-12 as cobalamin are NOT good options for MTHFR gene mutation. Instead, you can bypass mutated B vitamin pathways and take the already transformed version of the vitamin enzymes (Methylfolate for B-9 and Methylcobalamin for B-12 [may need to increment dosage]). View image.]

Options for additional B12 support: Hydroxy Mega Drops, Get B12 Spray, Black Bear Spray, Black Bear Drink, Adenosyl Mega drops, Methyl Mega drops, B12 injections (if possible hydroxyB12), Dibencozide (adensyl B12) tablets, Activated B12 Guard, Low dose B12 gum or B12 patch more limited support with cyanoB12 (as long as hydroxyl support in place)." [See: What's So Important about B12?]

Folate Ingestion — Map by Seeking Health™ - Methylation Badlands.pdf [Technical level]

Methylfolate types — Different Types of Methylfolate - Apples to Apples Ingredient Comparison — www.methyl-life.com/methylfolate-types.html & www.methyl-life.com/uploads/9/5/3/4/9534578/1331281_orig.jpg?703]

Finding the Link between Vitamin B12 and Neural Tube Defects — www.aacc.org/publications/strategies/archives/2009/Documents/043009CLS.pdf

Boron Borax — The Inexpensive Detox, Arthritis, Osteoporosis And Mycoplasma Cure — www.jbbardot.com/inexpensive-osteoporosis-mycoplasma/ The chemical names for Borax are Sodium Tetraborate, Disodium Tetraborate Decahydrate, or Sodium Borate.

Lithium — [See: LAB_TESTS_and_RESULTS]

Magnesium — www.functionalmedicineuniversity.com/public/882.cfm & Magnesium Deficiency — www.jigsawhealth.com/content/pdf/Magnesium_Deficiency_Report_Jigsaw_Health.pdf or Magnesium_Deficiency_Report_Jigsaw_Health.pdf

Magnesium L-Threonate reduces the amount of muscle twitching or fluttering under the skin, can help prevent and restore memory deficits especially for chronic neuropathic pain.

"Magnesium is an essential mineral for optimal metabolic function. Research has shown that the mineral content of magnesium in food sources is declining, and that magnesium depletion has been detected in persons with some chronic diseases." — www.homeopathyforwomen.org/supplements.htm

Salt (NaCl) — www.marksdailyapple.com/salt-what-is-it-good-for/#axzz2cqu6ClGp

Selenium — www.thyroidpharmacist.com/uploads/1/4/7/1/14712146/sample_chapter.pdf

"Selenium plays a very important role in thyroid function: 1) Acting as catalyst to convert the inactive T4 to the biologically active T3 2) Protecting thyroid cells from oxidative damage from hydrogen peroxide by forming selenoproteins. ... Studies have proposed that supplemental selenium could alleviate toxic effect of excessive iodine intake on the thyroid. Selenium is a trace mineral that is incorporated into proteins to make antioxidants like glutathione peroxidase. ... Selenium reduced the TgAb titers and increased the number of circulating T regulatory cells that help the immune system recognize itself and prevent the lymphocytic (WBC) infiltration of the thyroid cells that is present in autoimmune thyroiditis. ... [S]elenium intake protects against thyroid autoimmunity by acting as an antioxidant, and also has an effect on HLA-DR gene expression."

Why zinc is essential? — www.glutenfreesociety.org/product/ultra-zinc-gluten-free-immune-support/

Zinc and Copper imbalances — metabolichealing.com/michael-s-blog/zinc-and-copper-imbalances-immense-biochemical-implications/

Dehydroepiandrosterone (DHEA) ["DHEA, is a steroid hormone synthesized from cholesterol and secreted by the adrenal glands. ... DHEA is a very powerful precursor to all of your major sex hormones: estrogen, progesterone, and testosterone. (It's molecular structure is closely related to testosterone). We call it the 'mother hormone' — the source that fuels the body's metabolic pathway." www.womentowomen.com/adrenal-health-2/dhea-and-adrenal-imbalance/
"It functions as a precursor to male and female sex hormones, including testosterone and estrogen. Other claims range from benefits such as: Building up the adrenal gland; Strengthening the immune system; Slowing natural changes in the body that come with age; Providing more energy; Improving mood and memory; Building up muscle strength." www.webmd.com/diet/dhea-supplements
"This multifunctional hormone and its metabolite dehydroepiandrosterone sulfate (DHEA-S) provide critical hormonal benefits in both men and women (Traish 2011; Savineau 2013). As a precursor to androgens (male hormones) and estrogens (female hormones), DHEA plays a fundamental role in the maintenance of hormonal balance and youthful vitality. It also modulates a variety of pathways throughout the body involved in various aspects of health and disease via direct actions independent of its role as a precursor to androgens and estrogens (Samaras 2013; Traish 2011; Savineau 2013)." www.lef.org/protocols/metabolic_health/dhea_restoration_01.htm] Symptoms of low DHEA are: Extreme fatigue, Decrease in muscle mass, Decrease in bone density, Depression, Aching joints, Loss of libido and Lowered immunity.

S-Adenosyl methionine (SAM-e) (Other Names: Ademetionine, Adenosylmethionine, S-Adenosyl Methionine, S-Adenosylmethionine, S-Adenosylmethionine Butanedisulfonate, S-Adenosylmethionine Tosylate, S-Adenosylmethionine Tosylate Disulfate, SAM, SAM-e, SAMe, Sammy.) [SAMe is used for depression, anxiety, heart disease, fibromyalgia, osteoarthritis, bursitis, tendonitis, chronic lower back pain, dementia, Alzheimer's disease, slowing the aging process, chronic fatigue syndrome (CFS), improving intellectual performance, liver disease, Parkinson's disease, attention deficit-hyperactivity disorder (ADHD), multiple sclerosis (MS), spinal cord injury, seizures, migraine headache, and lead poisoning. Some women use SAMe for premenstrual syndrome (PMS) and a more severe form of PMS called premenstrual dysphoric disorder (PMDD).] — www.lmreview.com/articles/view/beyond-the-mitochondrial-tune-up-part-II

Ashwagandha Extract (for stress and hormone control)

[See: FUCOIDAN and DETOXIFICATION]

SCHISANDRA HERB - how to use and what it does. — Schisandra.pdf

Glutathione cycle for oxidation reduction (image) — bcn.boulder.co.us/health/rmeha/glut11.gif

*** The Mother Of All Antioxidants — www.collective-evolution.com/2014/04/13/the-mother-of-all-antioxidants/

"Glutathione is our body's most powerful antioxidant. It is a key biochemical in detoxifying the body of the heavy metals we encounter in the environment." — www.methyl-life.com/symptoms-of-mthfr.html and Things That Plague Us: Heavy Metals mthfrliving.com/ [Posted: April 19, 2014]

Glutathione foods — benefitsofglutathione.com/glutathione-foods/

COQ10 — www.begin2dig.com/2010/01/coq10-is-it-worth-it-from-athletic.html

Preventing Methylfolate Side Effects — mthfr.net/preventing-methylfolate-side-effects/2014/11/26/

NAC Supplementation (N-acetylcysteine) [The typical dosage of NAC given as an oral supplement in clinical trials is 600 mg b.i.d.] (Use the relatively stable synthetic cysteine derivative, N-acetylcysteine (NAC): — www.lmreview.com/articles/view/beyond-the-mitochondrial-tune-up-part-III

8 Medically Based Reasons You Should Be Consuming Coconut Every Single Day - Coconut oils are healthy — www.draxe.com/8-medically-based-reasons-consuming-coconut-every-single-day/

MTHFR - Nutritional Support and More! — www.homeopathyforwomen.org/MTHFR.htm#About_The_A1298C_Mutation

Chronic Lyme Disease: Myth or Reality? by Mehmet Oz, MD — www.oprah.com/health/Dr-Oz-Treating-Lyme-Disease ["Taking vitamin B12, coenzyme Q10, chromium, folate, omega-3 fatty acids, and herbs such as Rhodiola rosea can improve energy and help with cellular repair—all key in recovering from conditions that can be as resistant as Lyme disease."]

Functional nutrition perspective - The Institute for Functional Medicine — www.functionalmedicine.org/

Simplified Roadmap to Health — www.scribd.com/doc/132017201/Dr-Amy-s-Simplified-Road-Map-to-Health

Protect your liver — naturalsociety.com/4-ways-protect-liver-prescription-drugs/

Information on health effects of bananas — www.natureknows.org/2013/10/after-reading-this-youll-never-look-at.html

"(S)ubstances that are known to heal the gut, like L-glutamine, omega-3 fatty acids, zinc, antioxidants (in the form of vitamins A, C, and E), quercitin, aloe vera, and turmeric (for infections)." — breakingmuscle.com/nutrition/the-four-rs-how-to-restore-optimal-gut-health

"Recommended Foods and Supplements:
L-Glutamine - Helps to heal and seal the gut along with aiding in recovery after workouts, so it's a double whammy supplement.
Quality Fish Oil - Preferably a liquid, not capsule, if you can stand the taste. This helps reduce inflammation, balance hormones, and supports the immune system.
Probiotics - They provide live strains of good bacteria to help bolster your defenses.
Cinnamon - It can help to improve digestion and, as an added bonus, is great at balancing blood sugar levels. Mint - Great at soothing the stomach and can help to relax the gastrointestinal tract.
Zinc - Very important as it is utilized to form digestive enzymes and also used in regulating hormones.
Prebiotics - In the form of fermented foods. Prebiotics help to feed friendly bacteria and allow them to thrive in a healthy environment. Fermented foods include bio-available yogurt, kefir, kimchi, and sauerkraut.
PH Balancing or Alkaline Foods - Anything green is generally okay, like kale, spinach, broccoli, parsley, chlorella, and spirulina. These are all great at keeping high stomach acid levels in order."

AVOID CERTAIN FOODS: [See: GLUTEN]

Dairy (Lactose) Intolerance, Dairy Protein Intolerance: What It Is and How to Determine If You Have It — www.marksdailyapple.com/dairy-intolerance-what-it-is-and-how-to-determine-if-you-have-it/

Egg-substitute & egg-replacer (for those allergic to egg-albumen) — wholenewmom.com/recipes/energ-egg-substitute-egg-replacer-without-eggs/

Chronic Migraines - Solving the Mystery (Monosodium glutamate (MSG) is a guaranteed trigger for most patients) — www.livingwithout.com/issues/2_2/migrane_mystery-1312-1.html?s=FB082413

Energy Metabolism: The Good, The Bad, and In-Between — www.thehealthyhomeeconomist.com/energy-metabolism-the-good-the-bad-and-in-between/

The 12 rules of safe and effective weight loss — www.thehealthyhomeeconomist.com/the12-rules-of-safe-and-effective-weight-loss/

[See: HEART & CHOLESTEROL]

Prebiotics: The Complete Guide — simplygluten-free.com/glutenfreemagazine/learn/understanding-probiotics-prebiotics-the-complete-guide/

"Clinical and research data demonstrate that probiotics benefit people with chronic diarrhea and irritable bowel syndrome (IBS). Certain probiotic strains (Lactobacillus acidophilus, Lactobacillus casei, Lactococcus lactis) may help with the digestion of lactose, soy, and animal proteins (Lactobacillus plantarum). Probiotics (Lactobacillus salivarius, Bifidobacterium bifidus, Bifidobacterium lactis) can be used for the prevention of colon cancer and to lower cholesterol and blood pressure (Saccharomyces boulardii, Lactobacillus acidophilus, Lactobacillus casei). Another important aspect of probiotics (Saccharomyces boulardii, Lactobacillus acidophilus) is their ability to eradicate Helicobacter pylori (a microorganism causing ulcers) and to reduce symptoms of antibiotic-associated diarrhea due to Clostridium difficile. Recently, a particular probiotic, Bacillus coagulans, was shown to possess strong anti-inflammatory activity and benefit people with rheumatoid arthritis and ulcerative colitis. Finally, probiotics (Lactobacillus rhamnosus) can be used to treat various skin diseases like eczema. ... mannan-oligosaccharides or MOS, a product derived from the cell wall of the brewer's yeast, Saccharomyces cerevisiae." simplygluten-free.com

Prebiotics - fermented foods — simplygluten-free.com/glutenfreemagazine/learn/understanding-probiotics-prebiotics-the-complete-guide/ [See: What's So Important about B12? — wholenewmom.com/health-concerns/b12-deficiency-liver-pills-how-to-make-liver-pills/]

Kefir — a probiotic powerhouse — www.nourishingtreasures.com/index.php/2012/09/05/how-to-make-water-kefir-a-probiotic-powerhouse-photo-tutorial/

Kefir — users.chariot.net.au/~dna/kefirpage.html (open: Fermenting)

Kimchi — www.eatingoffthefoodgrid.com/a/index.htm (open: Fermenting)

Antibiotics and Dysbiosis - A conservative approach would follow a remove, repair and replace as well as a modified elimination diet and especially fructose elimination.

Wrong "Low-fat" diet destroys the body

What really causes heart disease, Dr. Dwight Lundell, M.D. (Author of: The Cure for Heart Disease: Truth Will Save a Nation and The Cure for Heart Disease and The Great Cholesterol Lie.) — myscienceacademy.org/2012/08/19/world-renown-heart-surgeon-speaks-out-on-what-really-causes-heart-disease/

"The only accepted therapy was prescribing medications to lower cholesterol and a diet that severely restricted fat intake. ... These recommendations are no longer scientifically or morally defensible. The discovery a few years ago that inflammation in the artery wall is the real cause of heart disease is slowly leading to a paradigm shift in how heart disease and other chronic ailments will be treated. The long-established dietary recommendations have created epidemics of obesity and diabetes, the consequences of which dwarf any historical plague in terms of mortality, human suffering and dire economic consequences. ... Simply stated, without inflammation being present in the body, there is no way that cholesterol would accumulate in the wall of the blood vessel and cause heart disease and strokes. Without inflammation, cholesterol would move freely throughout the body as nature intended. It is inflammation that causes cholesterol to become trapped. ... Inflammation is not complicated — it is quite simply your body's natural defence to a foreign invader such as a bacteria, toxin or virus. The cycle of inflammation is perfect in how it protects your body from these bacterial and viral invaders. However, if we chronically expose the body to injury by toxins or foods the human body was never designed to process, a condition occurs called chronic inflammation. Chronic inflammation is just as harmful as acute inflammation is beneficial. ...

*** "Let me repeat that: The injury and inflammation in our blood vessels is caused by the low fat diet recommended for years by mainstream medicine. ... There is no escaping the fact that the more we consume prepared and processed foods, the more we trip the inflammation switch little by little each day. The human body cannot process, nor was it designed to consume, foods packed with sugars and soaked in omega-6 oils." ***